Greetings, I had the exact same issues you are describing. I use nginx to reverse proxy to an application server backend running Windows+Apache+PHP. If keepalive_timeout was non-zero, PDF downloads would hang on our website. If we set it to zero, everything worked perfectly. However, we run all our sites on SSL exclusively; The overhead of doing SSL Negotiation for every single HTTP request wasby Slash - Nginx Mailing List - English
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