Hi,
Thanks for the explanation. It absolutely makes sense now that you've clarified how Nginx works.
Following on from this, I've now chosen to use HAProxy for this particular Exchange / Outlook Anywhere use-case.
This supports the 'streaming' model of Outlook Anywhere, by simply passing the data to the backend, without waiting for the complete body (with the 'option http-no-delay' directive - http://cbonte.github.com/haproxy-dconv/configuration-1.5.html#4-option%20http-no-delay).
I hope to be able to find a case for using Nginx in the future as it still looks like a great product.
Thanks again for the support,
Graham