We are currently using nginx as a proxy for a large number of sites but putting up a lot of rules to direct and traffic for each host. Is there a number of hosts ({server}) that would be too many for a single nginx instance to support? At what point does the configuration file get too large and start bogging down the nginx server? Currently each host takes up about 150 lines, and we are looking to put in 25+ hosts onto each server. Is this realistic?

Thanks for the advice.