my env:
nginx-0.8.45+php-5.3.6(php-fpm)+rhel 5.4

part of nginx conf:
#fastcg config
fastcgi_connect_timeout 5s;
fastcgi_send_timeout 5s;
fastcgi_read_timeout 5s;
fastcgi_buffer_size 4k;
fastcgi_buffers 256 4k;
fastcgi_busy_buffers_size 8k;
fastcgi_temp_file_write_size 16k;
fastcgi_intercept_errors on;
proxy_ignore_client_abort on;
php-fpm config:

pm = dynamic
pm.max_children = 300
pm.min_spare_servers = 25
pm.max_requests = 500
listen = 127.0.0.1:9000

rlimit_files = 102400
request_slowlog_timeout =1s
request_terminate_timeout = 5s
pm.status_path = /php_status


my server will serv 400req/s at peak. i found at that time ,php finished
process the request,but didn't push the output to the nginx
immediately(about 10 seconds,nginx got nothing from upstream(the php-fpm
)), it cause the client abort the request and make nginx responds with 499
error. the server seems at a fine load,enough ram,enough cpu,io is not high.
anyone has this situation?

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