My software stack:
CentOS 5.7
nginx 0.8.54 compiled
PHP 5.2.10
PHP-FPM

I have a doubt, if I update my php to php 5.3.3 or higher, Do I will need of PHP-FPM?

Thanks a lot.

PHP-FPM does not need a separate patch for 5.3 , its included into main PHP distribution

config file has been changed from XML to more traditional php.ini-like format