Hello,
Yes I have searched the request that generates this big size header, and it's a Get URI
pulling all the features installed and requested by the user of the ERP.

Before I integrate the uWSGI layer, the stack deployment with Nginx KTLS HTTP2 works perfectly and there's
no problem of buffer sizing.
The reason why I added the uWSGI layer, is for using the uwsgi-socket binary protocol, and it work fine and very fast
decreasing the time load for the principal web page.
So for now I have to switch to the http-socket protocol and configuring HTTP2 in uWSGI.
I hope in the future Nginx will allow using the huge headers sizing.

Thanks for your reply and clarifications.